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In the modern review, we claimed the identification as well as the characterization of a fresh atypical opioid receptor with exceptional unfavorable regulatory Homes towards opioid peptides.one Our results confirmed that ACKR3/CXCR7, hitherto often called an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is also a wide-spectrum scave